I've read a good chunk of this thread. Good stuff. I'm also from the Rochester/Buffalo area and agree with most of the statements. My favorite wing places in Buffalo are Bar Bill which is actually in East Aurora near the traffic circle. Duff's is my #2. They do traditional wings ideally. Rootie's near UB Amherst used to be great until they changed ownership in the late '90s, then they sucked and now I don't think the place is even there anymore. Good wings are everywhere though in Buffalo. The Anchor Bar is OK but overpriced presumably because it's a tourist trap. The wings are good but not spectacular.
I don't live there anymore but wings are growing in popularity and can be found elsewhere but it's hit and miss. Blondie's in NYC has good wings and I haven't heard anyone mention them. Haven't been to Quaker Steak & Lube but I hear they're good.
If you make your own wings, Frank's with some spices and Tobasco is good. Otherwise use a sauce called Wy's Wings sauce. I haven't had anything that compares to it. Their hot, called Wys Guy I think, is awesome because it has heat and flavor not just heat. The link is www.wyswings.com.
Their mild is excellent too although I don't eat it, my wife does. It's the tastiest mild I've ever had though easily.
I'm gonna order the Archie's sauce that someone recommended, but if it's as good as the Wys Wing sauces I'll be surprised. WW was at the Buffalo Wing Festival one year, maybe more than that I'm not sure. They sold them there. I didn't see them the next year though. I'm not sure if they were there last year or will be there this year or not. I get mine online.
Anyway, in Rochester the best wing places are McGregor's in the South Wedge, Jeremiah's as someone pointed out, the Sports Page, and Woody's has pretty good ones too. Hitchcock's now called the Merchant Street Grill or something had really good ones, but after the name change they didn't seem so great. I've only been there once since then so I'll give them another shot.
I make my own often now. They're better than the ones out easily where I live.