RE: Great seafood in or around Buffalo, N.Y.
Just adding some info to an old thread.... La Marina in Buffalo, on 1503 Hertel Ave., is pretty good for seafood. In fact, it could well be the only non-chain and non-sushi restaurant in Buffalo that focuses on seafood that's not fried.
If chains are okay with you, there's Red Lobster and Bonefish Grill out in the burbs, but I'm not sure how good they are.
There are several good sushi places in the Buffalo area, but Kuni's in the Elmwood District is the best and has the freshest seafood.
Fried seafood is quite popular in Buffalo, and the Friday fish fry has cult status there. Papa Jake's (1672 Elmwood) has a very good fish fry, but expect a long wait.