Not long ago, I ran back into the man who managed the Lum's here in Athens, Georgia. He remembered when my dad and I used to come in for lunch and - over a considerable period of time - drank our way "around the world," two beers at a time. Yep, my Dad turned me on to Guinness, and - proudly - I'll never be the same. Our Lum's burned down in a lightning-strike fire and was never rebuilt. There were two or three afterward around Atlanta, but they've all vanished now. (When I worked at Peaches Records there, we used to eat at the one across the street, which we dubbed "Glum's" because everyone who worked there was an utter sourpuss.)
Nobody's mentioned Shakey's Pizza Parlor! Used to be you could go there and sing corny old songs around a ricky-tick piano. The last one of those that I saw was on Stewart Avenue, S/W in Atlanta: it was open even after the one on Dickerson Pike in Nashville had closed: late 1980's.
Right down the road on Dickerson was the second last Minnie Pearl's Fried Chicken. Gracious, their food was so salty that I hardly could eat it. I'm sure it wasn't Mrs. Sarah Ophelia Colley's recipe! I hear tell that one remaining Minnie Pearl's is open in someplace like Bedford, Virginia.
Eddy Arnold also had a fried chicken joint chain at one time. Wonder if his was any better than Minnie Pearl's?
Fats Domino was associated in some capacity with a restaurant chain bearing his name seome years ago. Now Antoine (that's Mr. Domino's real name) can cook, mind you; he remains alive and well in the Ninth Ward of New Orleans at age 75, rocking and rolling with the best of them. - And boiling shrimps in a cauldron out in the yard!
Lastly, I'll mention Stan's Sandwich Shops. An outfit out of Jacksonville, Florida, they produced some of the most immemorable food I ever put into my mouth.
Still Here And Not Forgotten Myself, The Non-Chain-able, Non-Franchise-able Ort. Carlton in Athens, Georgia.