Hot Doug's (Chicago) »
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Peter Luger (NYC) » Cafe du Monde (New Orleans)
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Al's #1 Italian Beef (Chicago) » Langer's Deli (Los Angeles) » Graeter's
Prince's Hot Chicken Shack (Nashville) » In-N-Out » Pike Place Market (Seattle)
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Okay, I've been to a few. I'd go back to Cafe du Monde every day if I could. The others, not so much or at all.
I think because of the press some of these places get that you might want to try them at least once so that you'll be able to judge for yourself.... or say that you were there.
I'd add The Big Texan to the list. I was there last June and would go back if in the area. Not the best, but fun.
You have an In n Out in Santa Clarita... what do you think?