I guess the most famous is Yuengling.......I happen to love it and it is now available in the Columbus, OH area.
Their claim is that they're the oldest brewery in the USA. 1829 http://www.yuengling.com/our_story/
My Hometown, St. Marys, PA, boasts of it's fine Brew - Straub Beer! Not too far behind - 1872!
Straubs is made with no salts, no sugars and no preservatives - all natural! http://www.straubbeer.com/home.php
Straubs is available in the Columbus area also. Distributed by: http://www.heidelbergdistributing.com/?page=Columbus
You should be able to find it over there.
I'd be interested for you and your beer guzzling spouse to have a taste test between Yuengling and Straubs and see which one comes out on top!
If I was closer, I'd join you for a few Brewski's!
Let us know how it turns out after you sober up!