Northern VA to Ann Arbor via Pittsburg, and Toledo

Hey guys, its been a while since i have been on this forum, mainly due to a lack of travelling :( I am heading up to a wedding in Toledo and visiting a few friends in Ann Arbor from here in Northern VA.
Looks like:
Day 1 from here to Pittsburg, PA
Day 2 from Pittsburg, PA to Ann Arbor, MI
Day 3 Ann Arbor, MI to Toledo, OH
Day 4 Toledo, OH
Day 5 Toledo, OH back to Northern VA.
Any thing that I must have, besides a sandwich at the Permenti brother's? I dont mind going a little out of the way, mainly close to the coast on the way from Pittsburg, PA to and past Toledo, OH.
 
Thanks!

If you've not been to Tony Packo's (or even if you have) in Toledo you'd best get there before they close up shop. The word is a family feud is probably going to run them out of business.
 
In AA we love Blimpy Burger and Zingermann's Deli. Casey's Bar and Grill is also really good.
 
DT

If I had to suggest one place in my hometown of Pittsburgh, it would probably be Tessaro's for their burgers.

I like Primanti Brothers in Pittsburgh as well.  The downtown restaurant is a classic.

Thanks for the recommendations so far.