New York City & Boston June 2012

We are traveling by train, taking the 4 day Northern Canadian Route from Vancouver BC to Toronto this summer. I plan on renting a car and driving down to Buffalo/ Niagara Falls. From that point on it's up in the air, I am traveling with my wife and 11 yr old granddaughter. they have never been to New England, I was thinking of driving from Buffalo to Boston, is this a good idea ????? and a good route. What would you all do, if you were doing this. I want to get the best Roadfood travel route and also make it a fun trip and over night adventures for them. I will fly back to Washington State from whatever major New England city I end up in...........This will be the start of my trip report...................If Boston isn't a good idea, what do you think would be a good route???????.Thanks for the help in advance, all of you have been a great source of help to myself and my family.................Bill